On September 28th, 2026, Ana Rita Melo Ribeiro successfully defended her PhD in Textile Engineering at the University of Minho, with the thesis entitled “Functionalization of multi-layer halochromic patch with cinnamaldehyde-containing lipid nano carriers for preventing wound chronicity.”
Her research focused on the development of a multifunctional dressing combining antifungal activity with real-time monitoring of chronic wounds. The multilayer system integrates a pH-responsive halochromic layer containing anthocyanins with a bioactive layer incorporating cinnamaldehyde-loaded nanocarriers.
Produced through a combination of electrospinning and electrospray technologies, the dressing showed enhanced antifungal activity against Candida spp. and good cytocompatibility. Its pH-responsive colour changes also enabled non-invasive monitoring of wound status, combining therapeutic and sensing functions within a single platform.
The doctoral research was carried out under the supervision of Dr. Helena Felgueiras (2C2T, University of Minho), Professor Salette Reis (Requimte, University of Porto), and Dr. Catarina Seabra (Requimte, University of Porto).
The examination committee was chaired by Professor Dr. Raul Fangueiro (Department of Textile Engineering, University of Minho) and included Dr. Sónia Pinho (Escola Universitária Vasco da Gama), Dr. Cláudia Botelho (University of Porto), Dr. Graça Soares (Department of Textile Engineering, University of Minho) and Dr. Helena Felgueiras (2C2T, University of Minho).
Following the public presentation and discussion, the candidate successfully completed her PhD in Textile Engineering.
This research contributes to the development of a new generation of smart and multifunctional wound dressings, integrating therapeutic and monitoring functions within the same textile-based platform. By combining electrospun fibrous structures, natural pH-responsive compounds, and nanocarrier-mediated delivery of a natural antifungal agent, the work provides a promising strategy for addressing some of the major challenges associated with chronic wound management, particularly persistent fungal colonization and the need for frequent dressing removal.
The Centre for Textile Science and Technology congratulates Dr. Ana Rita Ribeiro on this important achievement and on her contribution to the development of innovative textile-based solutions for advanced wound care and biomedical applications.